You can certainly override anisotropy and multisample (FSAA) through the NV control panel, in which case the cvars in R1Q2 will have no effect.
How do you override anisotropic settings? My Nvidia Control panel (and I have the latest drivers) for "anisotropic filtering" says "application controlled"; or "off" or a number from 2 to 16x. I chose 16 x (does that automatically override r1gl settings, simply by choosing a number?Also, there is no FSAA setting per se in the Nvidia panel. There is an "antialiasing mode" setting. That can be set to "off"; "application controlled" ; "enhance the application setting" or "override". Should I set that to "override". Currently I have it set to "enhance the application setting"? I also have set the "antialiasing setting" option to "32x CSAA" in Nvidia. There is also an FXAA setting -- I have that set to "on".
so if you want adaptive or selective super-sampling, use your NV control panel and either enhance or override the application setting.